{"data":[{"source":"bio.acousti.ca","id":"57974","type":"article","title":"Traveling Waves on the Organ of Corti of the Chinchilla Cochlea: Spatial Trajectories of Inner Hair Cell Depolarization Inferred from Responses of Auditory-Nerve Fibers","author":"Temchin, A. N.; Recio-Spinoso, A.; Cai, H.; Ruggero, M. A.","editor":null,"year":"2012","month":null,"journal":null,"booktitle":null,"series":null,"howpublished":null,"volume":null,"number":null,"pages":null,"chapter":null,"edition":null,"publisher":null,"organization":null,"institution":null,"school":null,"address":null,"type_of_work":null,"note":null,"isbn":null,"issn":null,"doi":"10.1523\/JNEUROSCI.1138-12.2012","url":"http:\/\/www.jneurosci.org\/cgi\/doi\/10.1523\/JNEUROSCI.1138-12.2012","attachments":"https:\/\/bio.acousti.ca\/sites\/default\/files\/Traveling_Waves_on_the_Organ_of_Corti_of.pdf","keywords":null,"abstract":"Spatial magnitude and phase profiles for inner hair cell depolarization throughout the chinchilla cochlea were inferred from responses of auditory-nerve fibers to threshold- and moderate-level tones and tone complexes. Firing-rate profiles for frequencies \u2264 2 kHz are bimodal, with the major peak at the characteristic place and a secondary peak at 3\u20135 mm from the extreme base. Response- phase trajectories are synchronous with peak outward stapes displacement at the extreme cochlear base and accumulate 1.5-period lags at the characteristic places. High-frequency phase trajectories are very similar to the trajectories of basilar-membrane peak velocity toward scala tympani. Low- frequency phase trajectories undergo a polarity flip in a region, 6.5\u20139 mm from the cochlear base, where traveling-wave phase velocity attains a local minimum and a local maximum and where the onset latencies of near-threshold impulse responses computed from responses to near-threshold white noise exhibit a local minimum. That region is the same where frequency-threshold tuning curves of auditory-nerve fibers undergo a shape transition. Since depolarization of inner hair cells presumably indicates the mechanical stimulus to their stereocilia, the present results suggest that distinct low-frequency forward waves of organ of Corti vibration are launched simultaneously at the extreme base of the cochlea and at the 6.5\u20139 mm transition region, from where antiphasic reflections arise.","type_name":"Journal Article","journal_abbreviation":null,"pmid":null,"info_url":"https:\/\/bio.acousti.ca\/node\/57974"}]}